Cell Division
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  ReviewBuilding a better model of cancerAndriy Marusyk  and James DeGregori  Department of Biochemistry and Molecular Genetics, Department of Pediatrics, Integrated, Department of Immunology, Program in Molecular Biology, University of Colorado at Denver and Health Sciences Center, Aurora, CO 80045, USA  author email corresponding author email
Cell Division 2006,
1:24doi:10.1186/1747-1028-1-24
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| Published: |
18 October 2006 |
Abstract
The 2006 Cold Spring Harbor Laboratory meeting on the Mechanisms and Models of Cancer was held August 16–20. The meeting featured several hundred presentations of many short talks (mostly selected from the abstracts) and posters, with the airing of a number of exciting new discoveries. We will focus this meeting review on models of cancer (primarily mouse models), highlighting recent advances in new mouse models that better recapitulate sporadic tumorigenesis, demonstrations of tumor addiction to tumor suppressor inactivation, new insight into senescence as a tumor barrier, improved understanding of the evolutionary paths of cancer development, and environmental/immunological influences on cancer. | 
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