Cell Division

official impact factor 4.09

Open Access Review

Impact of steroid hormone signals on Drosophila cell cycle during development

Nicola Cranna and Leonie Quinn*

Author Affiliations

Department of Anatomy and Cell Biology, University of Melbourne, Parkville 3010, Melbourne, Australia

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Cell Division 2009, 4:3 doi:10.1186/1747-1028-4-3

Published: 20 January 2009

Abstract

Metamorphosis of Drosophila involves proliferation, differentiation and death of larval tissues in order to form the adult fly. The major steroid hormone implicated in the larval-pupal transition and adult tissue modelling is ecdysone. Previous reviews have draw together studies connecting ecdysone signaling to the processes of apoptosis and differentiation. Here we discuss those reports connecting the ecdysone pulse to developmentally regulated cell cycle progression.